RESEARCH ACTIVITIES

Health research has high value to society. It can provide important information about disease trends and risk factors, outcomes of treatment or public health interventions, functional abilities, patterns of care, and health care costs and use. Medical research can have an enormous impact on human health and longevity, and the resulting increased productivity of the population contributes greatly to the national economy  in addition to the individual benefits of improved health.
 
Lady Reading Hospital is a tertiary care hospital in Khyber Pukhtunkhwa province, Pakistan. It has, of recent, invested heavily in research activities. Research committees have been made which are streamlining the research activities. LRH is committed to excellence in research.

 

INSTITUTIONAL RESEARCH COMMITTEE

Prof Zahid Nazar

Dr. Faiz Ali Shah

Dr Ameer Muhammad

Dr. Fazl-e-wahid

Dr. Hamid Shehzad

Prof. Gul Rukh Qazi

Dr. Farnaz Zahoor

Dr Abdur Rehman

Dr Firaz Khan

INSTITUTIONAL REVIEW BOARD

Prof Rehana Rahim

Prof Zahid Nazar

Dr Saima Shehzadi

Dr Majid Paracha

Dr Muhammad Usman

Dr Anila Basit

Muhammad Ilyas

Dr. Nosheen Noor

Profile/Introduction

Dr. Habib Jan is an Assistant Professor Molecular Biology in the Department of Pathology, Lady Reading Hospital (MTI) Peshawar Pakistan. He holds a PhD in Genomics with distinction from Justus Liebig University Germany and a joint MS degree in Molecular & Statistical Genetics from Austria & France.

During his doctorate in Germany, he worked on the Genomic Predictions and Genome-wide Association Studies (GWAS) of complex traits. His PhD research was funded by the European Marie Curie Initial Training Network (MC-ITN) INTERCROSSING (Innovative Training Environment for Researchers Combining the Resources of Statistical Science, Informatics & Genetics). Dr. Jan has been working as a Team Lead in the Precision Medicine Lab at RMI Peshawar before joining the LRH. The title of the project was ‘Genomic investigation of oral cancer (Oral Squamous Cell Carcinoma; OSCC) in Pakistani population’.

Dr. Jan is a recipient of the European Erasmus Mundus Scholarship for his MS studies and European Marie-Skłodowska Curie Fellowship for his doctoral studies. He was awarded Bronze medals at his Bachelor and Masters studies, respectively. Dr. Jan was also involved in extra-curricular activities and was declared as Star Laureate (2006) by South Asia Publication (SAP), Karachi. He is also a member of the Erasmus Mundus Alumni Association, Marie- Skłodowska Curie Alumni Association and Genomics Society Pakistan.

Dr. Jan has published several scientific articles in the peer-reviewed international journals and has delivered many talks internationally. Dr. Jan is interested in the areas of genomics, big data and its role in human health. He intends to establish a Personalised Genomic Medicine Lab at Pathology Department, LRH-MTI in the future to work on genomics-enabled diagnostics and research in Pakistani populations. He is interested to supervise undergrad and postgraduate students interested in molecular biology, genetics & genomics.

Profile/Introduction

Dr. Ali Talha Khalil, has recently been appointed in the Department of Pathology, Lady Reading Hospital (MTI), as an Assistant Professor, Molecular Biology. He holds a PhD in Biotechnology from Quaid-i-Azam University, Islamabad. Dr. Ali Talha Khalil, research is based on the intersection of nanotechnology, biomaterials, nanomedicines and biotechnology. The primary focus of his research is the synthesis, designing and evaluation of nanomaterials for various medical and nanomedicine applications. This includes green synthesis of inorganic nanoparticles and novel nanostructures, keeping in view the principles of sustainability. There is a significant interest in using nanomaterials for applications in cancer, against drug resistant pathogens, viruses and in Alzheimer disease. Some of his recent work includes the investigation of the physicochemical properties and applications of green synthesized nanoceria and iron nanoparticles for potential therapeutic and nanomedicinal applications. There is also an interest in understanding the environmental and human health toxicity of nanomaterials. Besides, his core expertise, Dr. Ali Talha Khalil, has been working on the different lines like pharmacognosy, DNA barcoding, health security, bioethics and biosafety.

Dr. Ali Talha Khalil has extensively published in peer reviewed impact factor journals which has attracted more than 1900 citations with h-index and i10 index of 25 and 48 respectively (as of Nov. 2020). He has authored more than 80 international journal articles (Cumulative Impact Factor ~ 220), besides, 8 book chapters and a patent. He is a regular peer reviewer for various international journals. Due to his contributions in nanosciences, he was nominated as a Fellow of the UNESCO-UNISA Africa Chair in Nanosciences and Nanotechnology. He is also nominated in the flagship “UNESCO Youth As a Researcher”, initiative for conducting research on the mental health consequences of CoVID-19 in South Asian Youth. Recently, Dr. Ali Talha Khalil, was listed among the top 2% of the global influential scientists in their subfield disciplines according to the list prepared by the Stanford University, which is published in PLOS Biology.

Web links to his research gate and google scholar profiles: https://www.researchgate.net/profile/Ali_Khalil9 https://scholar.google.com.pk/citations?user=6z7BgZcAAAAJ&hl=en

Dr. Arshad Islam, PhD

Assistant Professor & Consultant – Biochemistry,

Department of Pathology,

Lady Reading Hospital

Medical Teaching Institution, Peshawar

 

Dr. Arshad Islam, has recently joined the Department of Pathology, Lady Reading Hospital Medical Teaching Institution (LRH/MTI) as an Assistant Professor & Consultant – Biochemistry.

Dr. Islam has earned his PhD in Biological Chemistry (Inorganic Biochemistry) from Universidade Federal de Minas Gerais (UFMG), Brazil, under the internationally competitive TWAS-CNPq Postgraduate Fellowship and M.Phil. in Biochemistry/Molecular Biology from Quaid-i-Azam University, Islamabad, under HEC-Indigenous Postgraduate Fellowships and BS (Hons) in Biotechnology from Centre of Biotechnology & Microbiology (COBAM), University of Peshawar. Moreover, Dr. Islam has worked as Post-doctoral Research Fellow at Postgraduate Program in Biological Sciences: Physiology and Pharmacology, UFMG, Brazil, for 3 years under the CAPES-PNPD and FAPEMIG Postdoctoral Fellowships in Immunopathology at the Nucleus of Research in Biological Sciences, Universidade Federal de Ouro Preto (UFOP), Brazil, for 1 year under the CAPES-CNPq Postdoctoral Fellowships.

His research interests, in general, include “Drug Discovery” and “Development of Nanoscale Drug Delivery Systems” with the purpose of improved drug’s potency and efficacy, aiming at the treatment of parasitic diseases such as Leishmania and Trypanosoma cruzi as well as cancer and bacterial infections using in vitro and in vivo models of the diseases. Furthermore, he has expertise in developing strategies to combat the currently prevalent microbial resistance against the clinically available drugs by modifying the existing drugs, encapsulating them into nanocarriers (liposome and surfactants specifically) to make them more efficacious and less toxic by improving their bioavailability through pharmacokinetics investigations of drugs.

He has also great expertise in the synthesis, physiochemical and morphological characterization of novel drugs and, chemically and biologically synthesized nanoparticles as well investigation of their efficacy, mechanism of action, related toxicities, therapeutic potential and, mechanism of resistance developed by the pathogens. He has gained expertise in the evaluation of

parasitic load in pathogenic parasite-targeted organs of infected animals after the treatment with novel drugs using q-PCR analysis, quantification of drug in the spleen and liver using EETA (atomic absorption) and other techniques, cytometric analysis to evaluate the apoptotic potential of drugs, necropsy of the experimental animal models as well as the use of HPLC and fluorescent microscopy techniques.

Furthermore, Dr. Islam has an excellent theoretical and experimental background in the fields of biochemistry, molecular biology and nanomedicine. His research experience also include the investigation on the “genetic and social factors associated with the cardiovascular diseases in Asian population”, using a number of biochemical and molecular techniques and screenings.

Dr. Islam has served as Assistant Professor – Biosciences at the Centre for Interdisciplinary Research in Basic Sciences, International Islamic University, Islamabad and has established a research lab “LeishInova”, where he has trained and supervised M.Phil and Ph.D research students. Dr. Islam has authored more than 14 research articles published in high impact international scientific journals and 1 book chapter in Royal Chemical Society. He is also a regular peer reviewer for various international journals.

Dr. Islam intends to establish a research lab at the Department of Pathology, where he may offer supervision to the postgraduate medical and research students, and is eager to establish research collaborations with national and international research institutions in order to enhance the research capacity of this institute.

Web link to google scholar profile: https://scholar.google.com.br/citations?user=chnvxSMAAAAJ&hl=en

Lady Reading Hospital

It was established in 1927and it is just 200 meters away in the south of the Grand Trunk Road, behind the famous historical Qila Balahisar. Famous MasjidMuhabat Khan,Ander Shehr bazaar, Qissa Khawani bazaar and Khyber bazaar is across the road of LRH. LRH is just outside historical wall in the jurisdiction of cantonment board. The anecdote of the hospital of its coming into being is that His Excellency Lord Reading, viceroy of India from 1921 to 1926, happened to visit Peshawar.

Lady Reading Hospital MTI

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